Queen Tiye was the Chief Queen of Amenhotep III. She was also the daughter of Tjuyu and Yuya and the mother of Akhenaten. She was considered to be the matriarch of the Amarna family.
Queen Tiye didn’t necessarily accomplish any momentous feat; rather she held a strong position in political life in Egypt. Her personality matched with her marriage to Amenhotep III induced her political strength which she used to benefit the empire.
No one knows how queen Tiye died. Some conspirators + Tiye wanted to kill the king (Ramesses III) to make Tiye’s son (Pentawer) king instead.
But the the conspirators were caught and were sent to trial, and were forced to commit suicide, all except for Queen Tiye.